Adoption nch
Patients without BPD were evaluated at routine follow-up visits in the neonatology outpatient clinic and patients with BPD were evaluated at the Comprehensive Center for BPD at NCH. Longer term outcomes included 18-month corrected composite scores on the Bayley Scales of Infant Development, third edition (BSID-III) assessment. Short-term outcome measurements included sO 2 at discharge and hospital length of stay. Comorbidities were assessed, including necrotizing enterocolitis (NEC) and intraventricular hemorrhage (IVH). Charts were reviewed and data obtained from all 424 patients who were born at 30 % and/or positive pressure support at 36 weeks PMA. This is a retrospective observational study. This study was approved by the Institutional Review Board of the Nationwide Children’s Hospital (NCH). Since BPD has been associated with poor neurodevelopmental outcome, we tested the hypothesis that the use of sO 2 at discharge from the NICU in extremely preterm neonates is associated with a greater risk of neurodevelopmental impairment (NDI) at 18 months corrected gestational age (CGA). Given the high incidence of BPD in this population, we examined the use of sO 2 at discharge to determine incidence and factors associated with sO 2 use at discharge. recently reported an incidence of 86 % in a Norwegian cohort of patients born between 22 and 27 completed weeks of gestation. Using this definition and the inverse relationship to gestational age, the incidence of BPD in the extremely preterm infant is very high. The emergence of “new” BPD and the improved survival of patients born at extremely early gestational ages led to a new definition of BPD from a National Institutes of Child Health and Human Development (NICHD) workshop. Over the decades, a “new” BPD has emerged that is characterized by fewer and larger alveoli, as well as decreased pulmonary microvasculature development. In 1967, Northway first described BPD as a requirement for supplemental oxygen (sO 2) at day of life (dol) 28 with chest X-ray findings demonstrating fibrosis and collapse surrounded by areas of marked hyperinflation. The strongest predictors of poor neurodevelopmental outcome in this population were prolonged positive pressure support, grade III–IV IVH, and discharge at >43 weeks PMA.īronchopulmonary dysplasia (BPD) is the most common chronic lung disease affecting preterm infants, and the incidence of BPD is inversely related to gestational age. Conclusions: The need for sO 2 at discharge is not associated with an increased risk of NDI in these patients. There was no difference in Bayley Scales of Infant Development, third edition composite scores between patients with no/mild BPD and patients with moderate/severe BPD (cognitive p = 0.60, communication p = 0.53, motor p = 0.19) or those scores between patients on and off oxygen at discharge (cognitive p = 0.58, communication p = 0.70, motor p = 0.62). Four hundred twenty-four charts were retrospectively reviewed from infants born at 43 weeks PMA (adjOR = 2.12, p = 0.04) were the strongest predictors of NDI at 18 months CGA. We tested the hypothesis that the use of supplemental oxygen (sO 2) at discharge from the NICU in extremely preterm neonates is associated with a greater risk of neurodevelopmental impairment (NDI) at 18 months corrected gestational age (CGA) than the risk of NDI of those neonates discharged in room air.